OXIDIZED NIFEDIPINE

Product Name: OXIDIZED NIFEDIPINE
CAS No.: 67035-22-7
Chemical Name: OXIDIZED NIFEDIPINE
Synonyms: B 4759;BAY-b-4759;Nifedipine-1;Dehydro Nifedipine;NIFEDIPINE EP IMP A;Nifidipine Impurity A;Nitrophenyl nifedipine;Nifedipine impurity A CRS;Nifedipine impurity A (EP);Divalproex Sodium Impurity 1
CBNumber: CB3505238
Molecular Formula: C17H16N2O6
Formula Weight: 344.32
MOL File: 67035-22-7.mol

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OXIDIZED NIFEDIPINE Property

Melting point:: 100-105 °C
Boiling point:: 443.7±45.0 °C(Predicted)
Density: 1.284±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: powder
pka: 1.55±0.29(Predicted)
color: yellow
EPA Substance Registry System: 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester (67035-22-7)

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Safety

Hazard Codes: Xi
Risk Statements: 41
Safety Statements: 26-39
WGK Germany: 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H318Causes serious eye damage
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: UC167
Product name: Oxidized Nifedipine
Purity: powder, ~95% (HPLC)
Packaging: 5mg
Price: $469
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1463600
Product name: Nifedipine Nitrophenylpyridine Analog
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1530
Updated: 2024/03/01

Cayman Chemical

Product number: 23229
Product name: Dehydro Nifedipine
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 23229
Product name: Dehydro Nifedipine
Purity: ≥98%
Packaging: 5mg
Price: $193
Updated: 2024/03/01

Sigma-Aldrich

Product number: UC167
Product name: Oxidized Nifedipine
Purity: powder, ~95% (HPLC)
Packaging: 10mg
Price: $861
Updated: 2024/03/01

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OXIDIZED NIFEDIPINE Chemical Properties,Usage,Production

Description

Dehydro nifedipine is an active metabolite of nifedipine , a calcium channel blocker present in formulations used to treat hypertension and angina. Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC₅₀ value of 130 μM.

Chemical Properties

Pale Yellow Solid

Uses

Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.

Uses

The main Nifedipine metabolite in human plasma

Definition

ChEBI: Dehydronifedipine is a phenylpyridine.

Biochem/physiol Actions

CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.

OXIDIZED NIFEDIPINE Preparation Products And Raw materials

Raw materials

Preparation Products

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OXIDIZED NIFEDIPINE Suppliers

Canada 2 China 89 France 2 India 7 Switzerland 1 United Kingdom 4 United States 11 Global 116

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

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View Lastest Price from OXIDIZED NIFEDIPINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Oxidized Nifedipine 67035-22-7
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2019-12-27

67035-22-7, OXIDIZED NIFEDIPINERelated Search:

Nifedipine METHYL 2-(O-NITROBENZYLIDENE)-ACETOACETATE Methyl 3-aminocrotonate 2,6-Ntp Dehydro Nifedipine N-Oxide diethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nifedipine Impurity J Hydroxydehydro Nifedipine Carboxylate methyl 2,4-bis{2-nitrophenyl}-6-methyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate Nifedipine Impurity 9 2,6-DIMETHYL-4-(3-NITRO-PHENYL)-PYRIDINE-3,5-DICARBOXYLIC ACID DIMETHYL ESTER Nifendipine Impurity G nifedipine iMpurity C Hydroxy Dehydro Nifedipine Lactone 3-aminocrotonamide Nifedipine impurity 10 Nifedipine EP IMpurity-B Nifedipine EP IMpurity-C

Nifedipine-1

Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridined

Nifedipine Impurity Ⅰ:2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester

2,6-Dimethyl-4-(2′-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester, Oxidized Nifedipine

Divalproex Sodium Impurity 1

Nifedipine Nitrophenylpyridine Analog

dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate

Nifedipine impurity A (EP)

Dimethyl 4-(2-nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

dimethyl2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate

2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester

B 4759

Dehydro Nifedipine

2,6-Dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid dimethyl ester

4-(2-Nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid dimethyl ester

BAY-b-4759

Nitrophenyl nifedipine

Nifedipine Impurity Ⅰ（Dimethyl 2,6-Dimethyl-4-(2-Nitrophenyl)pyridine-3,5-Dicarboxylate）

Nifedipine impurity A CRS

Dimethyl 2,6-Dimethyl-4-(2-nitrophe

Nifedipine EP Impurity A/Dehydro Nifedipine

3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-, 3,5-dimethyl ester

Nifidipine Impurity A

Nifedipine EP Impurity A (Nifedipine nitrophenylpyridine analogue)

Azilsartan medoxomil impurity308

DehydronifedipineQ: What is Dehydronifedipine Q: What is the CAS Number of Dehydronifedipine Q: What is the storage condition of Dehydronifedipine Q: What are the applications of Dehydronifedipine

Nifedipine Impurity Ⅰ:2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester

Nifedipine nitrophenylpyridine Analogue

dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate (nitrophenylpyridine analogue)

_x000b_Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridined

Nifedipine EP impurity A Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5- dicarboxylate (nitrophenylpyridine analogue)

NIFEDIPINE EP IMP A

67035-22-7

34432

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals